Clemson defeated SMU 34-31 in Week 15, covering the 3-point spread in a competitive contest that exceeded the over-under of 56 points.

The Tigers dominated early, jumping to a 21-7 first-quarter lead behind quarterback Cade Klubnik, who connected with Bryant Wesco Jr. for two touchdown passes of 43 and 35 yards. Clemson's offense controlled the first half before SMU mounted a fourth-quarter comeback, cutting the deficit to three points.

Klubnik led Clemson's passing attack with 262 yards. The high-octane first quarter featured multiple explosive plays, with SMU's defense recording several high-impact defensive stops early in the game. Despite the defensive struggles early, SMU fought back with Kevin Jennings scoring a rushing touchdown and later connecting with Matthew Hibner for a fourth-quarter touchdown reception.

The game remained competitive throughout, with two lead changes and a maximum win probability swing of 53.3 percentage points, indicating tight competition down the stretch. Hibner led SMU receivers with 69 yards, while Jennings rushed for 35 yards. Clemson's balanced offensive attack proved sufficient to secure the road victory.