Iowa overwhelmed UAlbany 34-7 in Week 1, controlling the game from start to finish. The Hawkeyes scored in every quarter, with touchdowns from Mark Gronowski's passing attack and Xavier Williams' rushing prowess setting the tone early. UAlbany's lone score came on a Jack Shields pass to Lasalle Rose Jr. in the second quarter, but Iowa's offense proved too potent to overcome.

Gronowski led Iowa's passing game with 44 completions, while Terrell Washington Jr. rushed for 69 yards. Seth Anderson led receivers with 9 catches. UAlbany managed only modest offensive success, with Shields leading a limited attack.

Iowa's defense made crucial plays throughout, including a fourth-quarter fumble recovery by Abdul Osholake that stalled a Hawkeye drive. The game followed a predictable script, with Iowa building a comfortable lead and never allowing UAlbany to threaten a comeback. The decisive victory set a strong tone for Iowa's season.