San Diego State cruised to a 24-7 victory over Wyoming in Week 10, with the Aztecs controlling most of the contest. The home team scored touchdowns in three of four quarters, opening with a 7-7 tie after the first quarter before pulling away with 10 points in the second quarter and adding another touchdown in the fourth.

Wyoming's lone score came early, matching San Diego State's first-quarter touchdown. However, the Cowboys managed just 7 total yards passing, with quarterback Kaden Anderson completing limited passes for 93 yards. The Aztecs' defense proved stifling, recording multiple interceptions in the second quarter that shifted momentum decisively in San Diego State's favor.

Lucky Sutton's 50-yard rushing touchdown in the fourth quarter punctuated the dominant performance. San Diego State's Christian Washington led all rushers with 9 carries, while Mikey Welsh paced the receiving corps with 7 catches.

The victory covered the spread as San Diego State exceeded their -9.5 point spread. The game finished well under the 42-point over-under, with the combined 31 points falling short of expectations for a relatively low-scoring affair.